The Assessment of Hemolysis and Renal Functions During and After Catheter Ablation for Atrial Fibrillation Using Pulsed-field Energy

Status: Recruiting
Intervention Type: Device
Study Type: Observational
SUMMARY

The aim of the project is to assess hemolysis and renal function after catheter ablation for atrial fibrillation using pulsed-field energy. Hemolysis will be determined using the concentration of red blood cell microparticles at the end of the ablation (when all ablation were done, before sheath removal). Hemoglobinuria will be assessed one day after the procedure. Renal functions will be assessed one and three day after the procedure using standard parameters (creatinine, urea). The goal is to assess the acute worsening fo renal functions after pulsed-field ablation in relation to the number of PF applications, and to the degree of immediate post-procedural hemolysis.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• symptomatic paroxysmal or non-paroxysmal atrial fibrillation

Time Frame
Start Date: 2024-05-01
Estimated Completion Date: 2024-12-30
Participants
Target number of participants: 100
Treatments
Pulsed-field ablation group
Patient with atrial fibrillation will undergo catheter ablation using pulsed-field energy
Sponsors
Leads: Charles University, Czech Republic

This content was sourced from clinicaltrials.gov